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狄乔治(顿颈骋别辞谤驳别)氏综合征相关蛋白抗体免 疫 原；KLH conjugated synthetic peptide derived from human DGCR14: 371-476/476
肾囊肿蛋白1抗体注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 By similarity. Does not seem to be strictly required for ciliogenesis By similarity. Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development. In connecting photoreceptor cilia influences the movement of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis By similarity.
二酰基甘油酰基转移酶2样蛋白6抗体免 疫 原；KLH conjugated synthetic peptide derived from human DGAT2L6: 165-270/337
肾连蛋白抗体注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.
二酰基甘油酰基转移酶2样蛋白4抗体免 疫 原；KLH conjugated synthetic peptide derived from human DGAT2L4: 251-333/333
神经前体细胞表达发育下调蛋白5抗体注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
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