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搁础狈结合蛋白2/核孔蛋白抗体
产物名称 | 英文名称 | 货号 |
RAN结合蛋白2/核孔蛋白抗体 | RanBP2 | GOY-01K2224 |
商品属性：
英文名称: RanBP2
中文名:RAN结合蛋白2/核孔蛋白抗体
别 名；Nuclear pore
complex protein Nup358; Nucleoporin 358; Nucleoporin Nup358; NUP358; P270; RAN
binding protein 2; Ran-binding protein 2; RANBP2; RBP2_HUMAN; Transformation
related protein 2; TRP 1; TRP 2; TRP1; TRP2; 358 kDa nucleoporin; E3
SUMO-protein ligase RanBP2.
研究领域；细胞生物 细胞周期蛋白 细胞分化 表观遗传学
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Cow, )
产物应用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；355kDa
细胞定位；细胞核 细胞浆
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human RanBP2: 1151-1350/3220
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
The nuclear pore complex protein, Ran-binding
protein 2 (Ran BP-2 or Nup358), contains four Ran-binding domains. Ran BP-2
is a large scaffold cyclophilin-related protein expressed in photoreceptor
cells. Ran BP-2 localization at cytoplasmic fibrils emanating from the
nuclear pore complex and interaction with the Ran-GTPase support its role in
nucleocytoplasmic transport processes. In humans, the Ran BP-2 gene is partially
duplicated in a gene cluster and lies in a hot spot for recombination on
chromosome 2q. This genetic heterogeneity renders further significance of
this genomic region in human disease due to its possible involvement in
genetically linked disorders such as juvenile nephronophthisis, congenital
hepatic fibrosis and chorioretinal dysplasia. E3 SUMO-protein ligase which facilitates SUMO1 and
SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP,
karyopherin)-mediated protein import via the F-G repeat-containing domain
which acts as a docking site for substrates. Could also have isomerase or
chaperone activity and may bind RNA or DNA. Component of the nuclear export
pathway. Specific docking site for the nuclear export factor exportin-1. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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