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磷酸化异染色质蛋白1抗体(果蝇)
产物名称 | 英文名称 | 货号 |
磷酸化异染色质蛋白1抗体(果蝇) | phospho-heterochromatin protein 1 (pTyr24) | GOY-01K2685 |
商品属性:
英文名称: phospho-heterochromatin protein
1 (pTyr24)
中文名:磷酸化异染色质蛋白1抗体(果蝇)
别 名;heterochromatin
protein 1 (phospho Tyr24); heterochromatin protein 1 (phospho Y24); Antigen
p25; Cbx 5; Cbx5; Chromobox homolog 5 (Drosophila HP1 alpha); Chromobox homolog
5 (HP1 alpha homolog Drosophila); Chromobox homolog 5; Chromobox protein
homolog 5; Chromobox protein homologue 5; Heterochromatin protein 1 alpha;
Heterochromatin protein 1; Heterochromatin protein 1 homolog alpha; HP 1; HP 1A;
HP1 alpha homolog; HP1A; HP1Hs alpha; HP1Hs-alpha.
产物类型;磷酸化抗体
研究领域;免疫学 染色质和核信号 昆虫
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted: Fruit Fly, )
产物应用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;23kDa
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated Synthesised phosphopeptide derived from Fruit Fly HP1 around the
phosphorylation site of Tyr24: EE(p-Y)AV
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
HP1 alpha is a component of heterochromatin. It
recognizes and binds histone H3 tails methylated at Lys-9, leading to
epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR).
This interaction can contribute to the association of the heterochromatin
with the inner nuclear membrane. HP1 proteins are relatively small proteins
(~25 kDa) with a conserved amino-terminal chromo domain and a structurally
related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1
are required for binding to native chromatin in vivo, but they contribute
differentially to binding in euchromatin and heterochromatin. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
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客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
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