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凋亡相关蛋白6抗体
产物名称 | 英文名称 | 货号 |
凋亡相关蛋白6抗体 | PDCD6 | GOY-01K2143 |
商品属性：
英文名称: PDCD6
中文名:凋亡相关蛋白6抗体
别 名；ALG 2; ALG2;
Apoptosis linked gene 2; Apoptosis linked gene 2 protein; Apoptosis-linked gene
2 protein; MA 3; MA3; MGC111017; MGC119050; MGC9123; PDCD 6; Pdcd6;
PDCD6_HUMAN; PEF 1B; PEF1B; Probable calcium binding protein ALG 2; Probable
calcium binding protein ALG2; Probable calcium-binding protein ALG-2;
Programmed cell death 6; Programmed cell death protein 6; PS 2; PS2.
研究领域；细胞生物 信号转导 细胞凋亡 转录调节因子 结合蛋白
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
产物应用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；22kDa
细胞定位；细胞核 细胞浆 细胞膜
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human PDCD6: 91-191/191
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
This gene encodes a calcium-binding protein
belonging to the penta-EF-hand protein family. Calcium binding is important
for homodimerization and for conformational changes required for binding to
other protein partners. This gene product participates in T cell receptor-,
Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for
this gene product, however, apoptosis was not blocked suggesting this gene
product is functionally redundant. Alternatively spliced transcript variants
encoding multiple isoforms have been observed for this gene, and a pseudogene
of this gene is also located on the short arm of chromosome 5. [provided by
RefSeq, May 2012]. Calcium-binding protein required for T-cell
receptor-, Fas-, and glucocorticoid-induced cell death. May mediate
Ca(2+)-regulated signals along the death pathway (By similarity).
Calcium-dependent adapter necessary for the association between PDCD6IP and
TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by
increasing caspase-3 activity. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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