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血清类粘蛋白1样蛋白1+2+3抗体
产物名称 | 英文名称 | 货号 |
血清类粘蛋白1样蛋白1+2+3抗体 | ORMDL1 + ORMDL2 + ORMDL3 | GOY-01K5510 |
商品属性:
英文名称: ORMDL1 + ORMDL2 + ORMDL3
中文名:血清类粘蛋白1样蛋白1+2+3抗体
研究领域;肿瘤 细胞生物 信号转导 新陈代谢
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted:
Human, Mouse, Rat, Chicken, Cow, )
产物应用;
not yet tested in
other applications.
optimal dilutions/concentrations
should be determined by the end user.
理论分子量;17kDa
细胞定位;细胞外基质 分泌型蛋白
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human ORMDL1 + ORMDL2 + ORMDL3:
1-80/153
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
The ORMDL (ORM1-like) family of proteins consist
of ORMDL1, ORMDL2 and ORMDL3; all of which are human homologs of the S.
cerevisiae ORM1 protein. Localized to the membrane of the endoplasmic
reticulum, ORMDLs are multi-pass membrane proteins that are implicated in
?secretase (BACE) function, as well as expression of Presenilin (PSI), a
protein involved in Alzheimer抯
disease (AD). ORMDL1 (ORM1-like protein 1), also known as Adoplin-1, is a
widely expressed 153 amino acid member of the ORMDL family. Expression of
ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a
therapeutic target for AD. ORMDL2 (ORM1-like protein 2), also known as
Adoplin-2, and ORMDL3 (ORM1-like protein 3) are expressed in tissues such as
heart, brain, lung, liver and kidney. ORMDL3 exists as two isoforms due to
alternative splicing events and may be a determinant of susceptibility to
childhood asthma Q9P0S3, Q53FV1, Q8N138 |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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