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麻豆媒体传播APP > 产物中心 > 蛋白/抗体 > 一抗 > 白细胞介素增强子结合因子3抗体

白细胞介素增强子结合因子3抗体

简要描述:白细胞介素增强子结合因子3抗体免 疫 原;KLH conjugated synthetic peptide derived from human ILF3: 1-100/894

  • 产物型号:GOY-01K5087
  • 厂商性质:科研
  • 更新时间:2023-10-24 00:00:00
  • 访&苍产蝉辫;&苍产蝉辫;问&苍产蝉辫;&苍产蝉辫;量:115

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白细胞介素增强子结合因子3抗体


产物名称

英文名称

货号

白细胞介素增强子结合因子3抗体

ILF3

GOY-01K5087

商品属性:

英文名称: ILF3

中文名:白细胞介素增强子结合因子3抗体

    名;CBTF; Double stranded RNA binding protein 76; Double-stranded RNA-binding protein 76; DRBF; DRBP76; ILF3; ILF3_HUMAN; Interleukin enhancer binding factor 3; Interleukin enhancer-binding factor 3; M phase phosphoprotein 4; M-phase phosphoprotein 4; MPHOSPH4; MPP4; NF AT 90; NF-AT-90; NF110; NF90; NFAR; Nuclear factor associated with dsRNA; Nuclear factor of activated T cells 90 kDa; Nuclear factor of activated T-cells 90 kDa; TCP80; Translational control protein 80

研究领域;细胞生物  转录调节因子  转运蛋白  表观遗传学

抗体来源;Rabbit

克隆类型;Polyclonal

交叉反应;(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )

产物应用;ELISA=1:5000-10000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量;95kDa

细胞定位;细胞核

    状;Liquid

    度;1mg/ml

免 疫 原;KLH conjugated synthetic peptide derived from human ILF3: 1-100/894

    型;IgG

纯化方法;affinity purified by Protein A

缓 冲 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产物介绍:

This gene encodes a double-stranded RNA (dsRNA)  binding protein that complexes with other proteins, dsRNAs, small noncoding  RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein  was first discovered to be a subunit of the nuclear factor of activated  T-cells (NFAT); a transcription factor required for T-cell expression of  interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the  larger of which is the product of this gene. These proteins have been shown  to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of  NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA  stabilization. In contrast, an isoform (NF110) of this gene that is  predominantly restricted to the nucleus has only minor effects on cell growth  when its levels are reduced. Alternative splicing results in multiple  transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]

May facilitate double-stranded RNA-regulated gene  expression at the level of post-transcription. Can act as a translation  inhibitory protein which binds to coding sequences of acid beta-glucosidase  (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA  translation, probably by inhibiting its binding to polysomes. Can regulate  protein arginine N-methyltransferase 1 activity. May regulate transcription  of the IL2 gene during T-cell activation. Can promote the formation of stable  DNA-dependent protein kinase holoenzyme complexes on DNA.

 

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