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白细胞介素增强子结合因子3抗体
产物名称 | 英文名称 | 货号 |
白细胞介素增强子结合因子3抗体 | ILF3 | GOY-01K5087 |
商品属性:
英文名称: ILF3
中文名:白细胞介素增强子结合因子3抗体
别 名;CBTF; Double stranded
RNA binding protein 76; Double-stranded RNA-binding protein 76; DRBF; DRBP76;
ILF3; ILF3_HUMAN; Interleukin enhancer binding factor 3; Interleukin
enhancer-binding factor 3; M phase phosphoprotein 4; M-phase phosphoprotein 4;
MPHOSPH4; MPP4; NF AT 90; NF-AT-90; NF110; NF90; NFAR; Nuclear factor
associated with dsRNA; Nuclear factor of activated T cells 90 kDa; Nuclear
factor of activated T-cells 90 kDa; TCP80; Translational control protein 80
研究领域;细胞生物 转录调节因子 转运蛋白 表观遗传学
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
产物应用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;95kDa
细胞定位;细胞核
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human ILF3: 1-100/894
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
This gene encodes a double-stranded RNA (dsRNA)
binding protein that complexes with other proteins, dsRNAs, small noncoding
RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein
was first discovered to be a subunit of the nuclear factor of activated
T-cells (NFAT); a transcription factor required for T-cell expression of
interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the
larger of which is the product of this gene. These proteins have been shown
to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of
NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA
stabilization. In contrast, an isoform (NF110) of this gene that is
predominantly restricted to the nucleus has only minor effects on cell growth
when its levels are reduced. Alternative splicing results in multiple
transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2008] May facilitate double-stranded RNA-regulated gene
expression at the level of post-transcription. Can act as a translation
inhibitory protein which binds to coding sequences of acid beta-glucosidase
(GCase) and other mRNAs and functions at the initiation phase of GCase mRNA
translation, probably by inhibiting its binding to polysomes. Can regulate
protein arginine N-methyltransferase 1 activity. May regulate transcription
of the IL2 gene during T-cell activation. Can promote the formation of stable
DNA-dependent protein kinase holoenzyme complexes on DNA. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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