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人类乳头状瘤病毒31 E7抗体
产物名称 | 英文名称 | 货号 |
人类乳头状瘤病毒31 E7抗体 | HPV31 E7 | GOY-01K1162 |
商品属性:
英文名称: HPV31 E7
中文名:人类乳头状瘤病毒31 E7抗体
别 名;VE7_HPV31;
Protein E7; E7; Human Papilloma Virus; Human papillomavirus type 31 E7; Human papillomavirus
type 31 (E7); Human papillomavirus type 31 E7; Human papillomavirus type 31 E7
protein; Protein E7; HPV31 E7 protein.
研究领域;肿瘤 免疫学 细菌及病毒
抗体来源;Rabbit
克隆类型;Polyclonal
产物应用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;11kDa
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from HPV31 E7 protein: 5-60/98
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
Human papilloma viruses (HPVs) can be classified
as either high risk or low risk according to their association with cancer.
HPV16 and HPV18 are the most common of the high risk group while HPV6 and
HPV11 are among the low risk types. Approximately 90% of cervical cancers
contain HPV DNA of the high risk types. Mutational analysis have shown that
the E6 and E7 genes of the high risk HPVs are necessary and sufficient for
HPV transforming function. The specific interactions of the E6 and E7
proteins with p53 and pRB, respectively, correlate with HPV high and low risk
classifications. The high risk HPV E7 proteins bind to pRB with a higher
affinity than do the low risk HPV proteins, and only the high risk HPV E6
proteins form detectable complexes with p53 in vitro. Human papillomaviruses
(HPV) are small DNA viruses which infect epithelia of the skin and mucosa.
Over 90 types have been identified and they mostly cause a variety of benign
lesions such as warts and verrucae. However, some subtypes, notably types 16
and 18, 31 and 33, have been confirmed as agents which cause cervical cancer. Function: |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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