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人乙肝病毒pre S1蛋白/HBV pre S1 protein抗体
产物名称 | 英文名称 | 货号 |
人乙肝病毒pre S1蛋白/HBV pre
S1 protein抗体 | HBV pre S1 protein | GOY-01K0096 |
商品属性：
英文名称: HBV pre S1 protein
中文名:人乙肝病毒pre S1蛋白/HBV pre
S1 protein抗体
别 名；Hepatitis B Virus
Surface Antigen; Hepatitis B virus S1/S2 protein; Hepatitis B virus PreS1;
Hepatitis B virus pre S1 protein; HBV pre S1 protein; HBSAG_HBVD2; HBSAG_HBVC5;
Hepatitis B Virus Major surface antigen; Large envelope protein; Large surface
protein; L glycoprotein; Major surface antigen; Large S protein; L-HBsAg; LHB.
研究领域；细胞生物 免疫学 细菌及病毒 细胞表面分子
抗体来源；Rabbit
克隆类型；Polyclonal
产物应用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；31/44kDa
细胞定位；细胞膜
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from Hepatitis B Virus Surface Antigen:
2-80/389
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
Hepatitis B Virus (HBV) infection induces a
disease state characterised by liver damage, inflammation and viral
persistence. Infection also increases the risk of hepatocellular carcinoma.
HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of
partially double stranded circular DNA. The DNA is enclosed in a
nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical
envelope (surface antigen or HBsAg). The core antigen shares its sequences
with the e antigen (HBeAg) but no cross reactivity between the two proteins
has been observed. The HBV genome also encodes a DNA polymerase that also
acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed
from serological tests that detect HBsAg but as the disease progresses this
antigen may no longer be present in the blood and tests for HBcAg are used.
If HBsAg can be detected in the blood for longer than six months, chronic
hepatitis B is diagnosed. The antigenic determinant of the protein moiety of
the HBsAg determines specific characteristics of different serotypes and
provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically,
two pairs of sub specific determinants, d/y and w/r allow the following
combinations: adw, ayw, adr, ayr. The large envelope protein exists in two
topological conformations, one which is termed 'external' or Le-HBsAg and the
other 'internal' or Li-HBsAg. In its external conformation the protein
attaches the virus to cell receptors and thereby initiating infection. This
interaction determines the species specificity and liver tropism. This
attachment induces virion internalization predominantly through
caveolin-mediated endocytosis. The large envelope protein also assumes fusion
between virion membrane and endosomal membrane (Probable). In its internal
conformation the protein plays a role in virion morphogenesis and mediates
the contact with the nucleocapsid like a matrix protein. The middle envelope protein plays an important
role in the budding of the virion. It is involved in the induction of budding
in a nucleocapsid independent way. In this process the majority of envelope
proteins bud to form subviral lipoprotein particles of 22 nm of diameter that
do not contain a nucleocapsid. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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