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甘氨酰胺核苷酸合成酶重组兔单克隆抗体
产物名称 | 英文名称 | 货号 |
甘氨酰胺核苷酸合成酶重组兔单克隆抗体 | GART | GOY-01K1213 |
商品属性:
英文名称: GART
中文名:甘氨酰胺核苷酸合成酶重组兔单克隆抗体
别 名;5'-phosphoribosylglycinamide
transformylase; AIR synthase; AIRS; GAR transformylase; GARS; GARTF;
Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT;
Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylglycinamide
formyltransferase; Phosphoribosylglycinamide formyltransferase
phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase;
Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29;
Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide
synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide
synthetase; PRGS; PUR2_HUMAN; Trifunctional purine biosynthetic protein
adenosine 3.
研究领域;肿瘤 细胞生物 信号转导 新陈代谢 表观遗传学
抗体来源;Rabbit
克隆类型;Monoclonal
交叉反应;(predicted:
Human, Mouse, Rat, )
产物应用;WB=1:500
IHC-P=1:100-500 ICC=1:50-200 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;107kDa
细胞定位;细胞浆
性 状;Liquid
浓 度;1mg/ml
免 疫 原;Recombinant
Human GART protein : 570-750/1010
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
Purines are critical for energy metabolism, cell
signaling and cell reproduction and also function as precursors for
coenzymes, energy transfer molecules, regulatory factors and proteins
involved in RNA and DNA synthesis. GART (GAR transformylase), also referred
to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length
and is a key folate-dependent trifunctional enzyme with
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide
synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity
required for de novo purine biosynthesis. Cancer cells require considerable
amounts of purines to sustain their accelerated growth and GART is,
therefore, a target for cancer chemotherapy. GART is highly conserved in
vertebrates. Two isoforms of GART are expressed due to alternative splicing
events. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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