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叉头蛋白滨1抗体
产物名称 | 英文名称 | 货号 |
叉头蛋白I1抗体 | FOXI1 | GOY-01K1496 |
商品属性：
英文名称: FOXI1
中文名:叉头蛋白I1抗体
别 名；FKH10; FKHL10; Forkhead
(Drosophila) like 10; Forkhead box I1; Forkhead box protein I1; Forkhead like
10; Forkhead related activator 6; Forkhead related transcription factor 6;
Forkhead-related protein FKHL10; FREAC 6; FREAC6; Hepatocyte nuclear factor 3
forkhead homolog 3; HFH 3; HFH3; HNF 3/fork head homolog 3; HNF-3 fork-head
homolog 3; Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds; MGC34197;
FOXI1_HUMAN.
研究领域；神经生物学 转录调节因子 表观遗传学
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
产物应用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；41kDa
细胞定位；细胞核
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human FOXI1: 101-200/378
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
FOXI1 is a member of the FOX family of
transcription factors. The FOX family is a large group of proteins
(consisting of at least 43 members) that share a common DNA binding domain
termed winged-helix or forkhead domain. FOX transcription factors play
important roles in development, differentiation, aging and hormone
responsiveness. Localizing to the nucleus, FOXI1 functions as a transcription
factor. Mice with mutated forms of FOXI1 show defects in ear development,
implying that FOXI1 plays a significant role in the developmental pathway of
ears and, in particular, the cochlea and vestibulum. FOXI1 is an upstream
transcription regulator of Pendrin (a protein associated with deafness),
suggesting a role for FOXI1 in the pathogenesis of Pendred syndrome (PS), a
condition of nonsyndromic hearing loss and enlarged vestibular aqueduct
(EVA). FOXI1 belongs to the forkhead family of
transcription factors which are characterized by a distinct forkhead domain.
This gene may play an important role in the development of the cochlea and
vestibulum, as well as embryogenesis. Mutations in this gene may be
associated with the common cavity phenotype. Two transcript variants encoding
different isoforms have been found for this gene. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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