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脂肪酸脱氢酶2抗体
产物名称 | 英文名称 | 货号 |
脂肪酸脱氢酶2抗体 | FADS2 | GOY-01K0344 |
商品属性:
英文名称: FADS2
中文名:脂肪酸脱氢酶2抗体
别 名;D6D; Delta(6)
desaturase; Delta(6) fatty acid desaturase; DES 6; DES6; FADS 2; FADSD 6;
FADSD6; Fatty acid desaturase 2; linoleoyl-CoA desaturase (delta-6-desaturase)
like 2; LLCDL 2; LLCDL2; SLL0262; TU 13; TU13; FADS2_HUMAN.
研究领域;肿瘤 心血管 免疫学 神经生物学 激酶和磷酸酶
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;Mouse, (predicted: Human, Rat, Chicken,
Pig, Cow, Horse, Rabbit, )
产物应用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;52kDa
细胞定位;细胞浆 细胞膜
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human FADS2: 221-300/444
亚 型;IgG
纯化方法;affinity
purified by Protein A
保存条件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
Members of the fatty acid desaturase (FADS)
family, including FADS1, FADS2 and FADS3, regulate the desaturation of fatty
acids by introducing double bonds between defined carbons of fatty acyl
chains, thereby playing an essential role in the lipid metabolic pathway.
Members of this family share N-terminal cytochrome b5-like domains,
C-terminal multiple membrane-spanning desaturase regions and 3 histidine box
motifs. FADS2 (fatty acid desaturase 2), also known as D6D, DES6, LLCDL2 or
TU13, is a 444 amino acid multi-pass membrane protein that localizes to the
endoplasmic reticulum and contains one cytochrome b5 heme-binding domain.
Expressed in adult and fetal heart and in adult liver, brain, lung and
retina, FADS2 functions as a component of a lipid metabolic pathway and
catalyzes the first step in the pathway, namely the formation of unsaturated
fatty acids from polyunsaturated fatty acids. Defects in the gene encoding
FADS2 are the cause of cause of fatty acid delta-6-desaturase deficiency, an
affliction that is characterized by skin abnormalities, corneal ulceration
and growth failure. Multiple isoforms of FADS2 exist due to alternative
splicing events. Function: FADS2 (Fatty acid desaturase 2) catalyses the
biosynthesis of highly unsaturated fatty acids from precursor essential
polyunsaturated fatty acids (linoleic and alpha-linoleic acid). FADS family
members comprise an N-terminal cytochrome b5-like domain and a C-terminal
membrane-spanning desaturase. FADS2 is repressed by dietary highly
unsaturated fatty acids. Altered expression of FADS2 may be associated with
obesity-associated insulin resistance. Genetic studies have linked FADS2 to
IQ and attention-deficit/hyperactivity disorder (ADHD). |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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