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皮肤罢细胞淋巴瘤相关抗原5抗体
产物名称 | 英文名称 | 货号 |
皮肤T细胞淋巴瘤相关抗原5抗体 | CTAGE5 | GOY-01K1981 |
商品属性：
英文名称: CTAGE5
中文名:皮肤T细胞淋巴瘤相关抗原5抗体
别 名；cTAGE 5A; cTAGE
5B; cTAGE 5C; cTAGE 5D; cTAGE family member 5; CTAGE family, member 5; cTAGE5A;
cTAGE5B; cTAGE5C; cTAGE5D; CTGE5_HUMAN; Cutaneous T cell lymphoma associated
antigen 5; Cutaneous T-cell lymphoma-associated antigen 5; MEA11; MEA6;
Meningioma expressed antigen 6 (coiled coil proline rich); Meningioma expressed
antigen 6/11; Meningioma-expressed antigen 6/11; MGEA; MGEA11; MGEA6; Protein
cTAGE 5; Protein cTAGE-5.
研究领域；肿瘤 细胞生物 免疫学 淋巴细胞 t-淋巴细胞 肿瘤细胞生物标志物
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, )
产物应用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；91kDa
细胞定位；细胞浆
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human CTAGE5: 268-360/804
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
Cutaneous T cell lymphomas (CTCL) represent a
group of malignancies that originate from CD4-T lymphocytes and manifest on
the skin. CTCL is a general term for several neoplasms including mycosis
fungoides, T cell leukemia/ lymphoma and pagetoid reticulosis, all of which
are very difficult to treat in the advanced stages. CTAGE2 (cutaneous T cell
lymphoma associated-antigen 2) is a member of the cancer/testis antigen
family of proteins (CTAGE) that, under normal conditions, are found primarily
in the testis with little or no expression in other parts of the body.
Another member of the CTAG family, namely CTAGE5 (also known as MEA11, MEA6,
MGEA11 or MGEA6), is a tumor associated antigen that is found in tumors of
various origins, including cutaneous T cell lymphomas. Both CTAGE2 and CTAGE5
are expressed as multiple isoforms due to alternative splicing events. Tumor-associated antigen.Tissue
specificity:Isoform 5A is expressed only in testis (at the protein level).
Other isoforms are expressed in several other normal tissues, including
brain, muscle and cranial skin. Isoform 5A (at protein level) and isoform 5B
are expressed in cutaneous T-cell lymphoma (CTCL) cell lines, colorectal
carcinomas, breast carcinomas and melanoma. Isoform 5B, but not isoform 5A,
is expressed in head and neck squamous cell carcinoma. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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