欢迎来到麻豆媒体传播APP网站！
咨询电话：18321818584欢迎来到麻豆媒体传播APP网站！咨询电话：18321818584
产物分类
Product Category相关文章
Related Articles详细介绍
剪切和多聚腺苷酸化特异性因子73蛋白抗体
产物名称 | 英文名称 | 货号 |
剪切和多聚腺苷酸化特异性因子73蛋白抗体 | CPSF73 | GOY-01K0437 |
商品属性：
英文名称: CPSF73
中文名:剪切和多聚腺苷酸化特异性因子73蛋白抗体
别 名；Cleavage and
polyadenylation specific factor 3 73kDa; Cleavage and polyadenylation
specificity factor 73 kDa subunit; Cleavage and polyadenylation specificity
factor subunit 3; CPSF 73; CPSF 73 kDa subunit; CPSF; CPSF-73; cpsf3;
CPSF3_HUMAN; CPSF73; YSH1.
研究领域；细胞生物 结合蛋白 表观遗传学
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产物应用；WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；77kDa
细胞定位；细胞核
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human CPSF73: 51-150/684
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
This gene encodes a member of the
metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the
cleavage and polyadenylation specificity factor and functions as an
endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to
polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during
histone 3'-end pre-mRNA processing. [provided by RefSeq, Oct 2012] Component of the cleavage and polyadenylation
specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end
formation, recognizing the AAUAAA signal sequence and interacting with
poly(A) polymerase and other factors to bring about cleavage and poly(A)
addition. Has endonuclease activity, and functions as mRNA 3'-end-processing
endonuclease. Also involved in the histone 3'-end pre-mRNA processing. U7
snRNP-dependent protein that induces both the 3'-endoribonucleolytic cleavage
of histone pre-mRNAs and acts as a 5' to 3' exonuclease for degrading the
subsequent downstream cleavage product (DCP) of mature histone mRNAs.
Cleavage occurs after the 5'-ACCCA-3' sequence in the histone pre-mRNA
leaving a 3'hydroxyl group on the upstream fragment containing the stem loop
(SL) and 5' phosphate on the downstream cleavage product (DCP) starting with
CU nucleotides. The U7-dependent 5' to 3' exonuclease activity is processive
and degrades the DCP RNA substrate even after complete removal of the
U7-binding site. Binds to the downstream cleavage product (DCP) of histone
pre-mRNAs and the cleaved DCP RNA substrate in a U7 snRNP dependent manner. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
产物咨询
电话
微信扫一扫
联系人：销售部
地址：上海市嘉定区澄浏公路52号盛创公司
邮箱：3004918891蔼辩辩.肠辞尘
手机：18321818584 / 15026555973