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颁顿98重链抗原抗体
产物名称 | 英文名称 | 货号 |
CD98重链抗原抗体 | CD98 | GOY-01K0170 |
商品属性：
英文名称: CD98
中文名:CD98重链抗原抗体
别 名；4F2; 4F2 cell
surface antigen heavy chain; 4F2 cell-surface antigen heavy chain; 4F2 heavy
chain; 4F2 heavy chain antigen; 4F2_HUMAN; 4F2hc; 4T2HC; Antigen defined by
monoclonal antibody 4F2 heavy chain; Antigen identified by monoclonal
antibodies 4F2 TRA1.10 TROP4 and T43; CD 98; CD98 antigen; CD98 heavy chain;
CD98HC; Heavy chain; Lymphocyte activation antigen 4F2 large subunit; MDU 1;
MDU1; Monoclonal antibody 44D7; NACAE; Slc3a2; Solute carrier family 3
(activators of dibasic and neutral amino acid transport) member 2; Solute
carrier family 3 member 2.
研究领域；细胞生物 免疫学 信号转导 干细胞 转录调节因子 t-淋巴细胞 b-淋巴细胞
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, )
产物应用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；69kDa
细胞定位；细胞浆 细胞膜
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH conjugated
synthetic peptide derived from human CD98: 231-280/630 <Extracellular>
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
This gene is a member of the solute carrier family
and encodes a cell surface, transmembrane protein. The protein exists as the
heavy chain of a heterodimer, covalently bound through di-sulfide bonds to
one of several possible light chains. The encoded transporter plays a role in
regulation of intracellular calcium levels and transports L-type amino acids.
Alternatively spliced transcript variants, encoding different isoforms, have
been characterized. [provided by RefSeq, Nov 2010]. Function: Required for the function of light chain
amino-acid transporters. Involved in sodium-independent, high-affinity
transport of large neutral amino acids such as phenylalanine, tyrosine,
leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1
and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts
as an arginine/glutamine exchanger, following an antiport mechanism for amino
acid transport, influencing arginine release in exchange for extracellular
amino acids. Plays a role in nitric oxide synthesis in human umbilical vein
endothelial cells (HUVECs) via transport of L-arginine. Required for normal
and neoplastic cell growth. When associated with SLC7A5/LAT1, is also
involved in the transport of L-DOPA across the blood-brain barrier, and that
of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell
membrane in tissues such as placenta. Involved in the uptake of methylmercury
(MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and
hence plays a role in metal ion homeostasis and toxicity. When associated
with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular
weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine
(L-CNSO) across the transmembrane. Together with ICAM1, regulates the
transport activity LAT2 in polarized intestinal cells, by generating and
delivering intracellular signals. When associated with SLC7A5, plays an
important role in transporting L-leucine from the circulating blood to the
retina across the inner blood-retinal barrier. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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