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22号染色体开放阅读框28抗体
产物名称 | 英文名称 | 货号 |
22号染色体开放阅读框28抗体 | C22orf28 | GOY-01K0205 |
商品属性:
英文名称: C22orf28
中文名:22号染色体开放阅读框28抗体
别 名;FAAP; Ankyrin
repeat domain 54; C22orf28; Chromosome 22 open reading frame 28; DJ149A16.6;
HSPC117; Hypothetical protein LOC51493; Novel protein HSPC117; RP1-149A16.6;
RTCB_HUMAN; tRNA-splicing ligase RtcB homolog.
研究领域;细胞生物 免疫学 神经生物学
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
产物应用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;55kDa
细胞定位;细胞浆
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human HSPC117/C22orf28: 411-505/505
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
HSPC117, also known as C22orf28, is a 505 amino
acid protein that is encoded by a gene which maps to human chromosome 22. A
highly homologous protein identified in rodents, FAAP (focal adhesion
associated protein), encoded by murine D10Wsu52e gene, has been suggested to
play a role in regulating cell adhesion dynamics. Chromosome 22 houses over
500 genes and is the second smallest human chromosome. Mutations in several
of the genes that map to chromosome 22 are involved in the development of
Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Additionally, translocations between chromosomes 9 and 22 may lead to the
formation of the Philadelphia Chromosome and the subsequent production of the
novel fusion protein BCR-Abl, a potent cell proliferation activator found in
several types of leukemias. Function: Catalytic subunit of the tRNA-splicing ligase
complex that acts by directly joining spliced tRNA halves to mature-sized
tRNAs by incorporating the precursor-derived splice junction phosphate into
the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase
with broad substrate specificity, and may function toward other RNAs. |
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客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
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我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
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